Generation of transgenic mouse line with prostate-specific expression of codon-improved Cre recombinase

BACKGROUND: Genetically engineered mouse models are useful tools to decipher molecular mechanisms of diseases. As for prostates, a rat probasin promoter has been widely used to drive prostate-specific gene expression. To optimize its codon usage to that of mammals, we used codon-improved Cre recombi...

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Опубликовано в: :Prostate Int
Главные авторы: Kanayama, Mayuko, Nakao, Kazuki, Horie, Shigeo, Aiba, Atsu
Формат: Artigo
Язык:Inglês
Опубликовано: Asian Pacific Prostate Society 2018
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6104291/
https://ncbi.nlm.nih.gov/pubmed/30140659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prnil.2018.04.003
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