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Generation of an inducible RPE-specific Cre transgenic-mouse line

The retinal pigment epithelium (RPE) is an epithelial monolayer in the back of the vertebrate eye. RPE dysfunction is associated with retinal degeneration and blindness. In order to fully understand how dysregulation affects visual function, RPE-specific gene knockouts are indispensable. Since the c...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Schneider, Sandra, Hotaling, Nathan, Campos, Maria, Patnaik, Sarita Rani, Bharti, Kapil, May-Simera, Helen Louise
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237357/
https://ncbi.nlm.nih.gov/pubmed/30440011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0207222
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