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Selection of primary cell cultures with cre recombinase induced somatic mutations from transgenic mice.
Deletion of genes in defined cell types has been achieved using a combination of gene targeting techniques and the Cre- lox P recombination system. Here we present a method to selectively isolate genetically altered primary cell cultures based on the permanent activation of a drug-resistance gene by...
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Main Authors: | , , , |
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Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
1998
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC147834/ https://ncbi.nlm.nih.gov/pubmed/9722652 |
Clibeanna: |
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