Selection of primary cell cultures with cre recombinase induced somatic mutations from transgenic mice.
Deletion of genes in defined cell types has been achieved using a combination of gene targeting techniques and the Cre- lox P recombination system. Here we present a method to selectively isolate genetically altered primary cell cultures based on the permanent activation of a drug-resistance gene by...
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| Опубликовано в:: | Nucleic Acids Res |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
1998
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147834/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9722652/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.18.4301 |
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