From ab initio quantum mechanics to molecular neurobiology: A cation–π binding site in the nicotinic receptor

The nicotinic acetylcholine receptor is the prototype ligand-gated ion channel. A number of aromatic amino acids have been identified as contributing to the agonist binding site, suggesting that cation–π interactions may be involved in binding the quaternary ammonium group of the agonist, acetylchol...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Zhong, Wenge, Gallivan, Justin P., Zhang, Yinong, Li, Lintong, Lester, Henry A., Dougherty, Dennis A.
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1998
Assuntos:	Physical Sciences
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22789/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9770444/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.21.12088
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