From ab initio quantum mechanics to molecular neurobiology: A cation–π binding site in the nicotinic receptor
The nicotinic acetylcholine receptor is the prototype ligand-gated ion channel. A number of aromatic amino acids have been identified as contributing to the agonist binding site, suggesting that cation–π interactions may be involved in binding the quaternary ammonium group of the agonist, acetylchol...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1998
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22789/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9770444/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.21.12088 |
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