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From ab initio quantum mechanics to molecular neurobiology: A cation–π binding site in the nicotinic receptor

The nicotinic acetylcholine receptor is the prototype ligand-gated ion channel. A number of aromatic amino acids have been identified as contributing to the agonist binding site, suggesting that cation–π interactions may be involved in binding the quaternary ammonium group of the agonist, acetylchol...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Zhong, Wenge, Gallivan, Justin P., Zhang, Yinong, Li, Lintong, Lester, Henry A., Dougherty, Dennis A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 1998
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22789/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9770444/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.21.12088
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