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Interaction between the RGS domain of RGS4 with G protein α subunits mediates the voltage-dependent relaxation of the G protein-gated potassium channel

1. In native cardiac myocytes, there is a time dependence to the G protein-gated inwardly rectifying K(+) (K(G)) channel current during voltage steps that accelerates as the concentration of acetylcholine is increased. This phenomenon has been called ‘relaxation’ and is not reproduced in the reconst...

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Main Authors: Inanobe, Atsushi, Fujita, Satoru, Makino, Yasunaka, Matsushita, Kenji, Ishii, Masaru, Chachin, Motohiko, Kurachi, Yoshihisa
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278761/
https://ncbi.nlm.nih.gov/pubmed/11507164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2001.t01-1-00133.x
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