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Mechanism of Ba(2+) block of a mouse inwardly rectifying K(+) channel: differential contribution by two discrete residues
1. The block of the IRK1/Kir2.1 inwardly rectifying K(+) channel by a Ba(2+) ion is highly voltage dependent, where the ion binds approximately half-way within the membrane electrical field. The mechanism by which two distinct mutations, E125N and T141A, affect Ba(2+) block of Kir2.1 was investigate...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Blackwell Science Inc
2001
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2278702/ https://ncbi.nlm.nih.gov/pubmed/11454958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2001.00381.x |
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