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The Pore Helix Dipole Has a Minor Role in Inward Rectifier Channel Function
Ion channels lower the energetic barrier for ion passage across cell membranes and enable the generation of bioelectricity. Electrostatic interactions between permeant ions and channel pore helix dipoles have been proposed as a general mechanism for facilitating ion passage. Here, using genetic sele...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3017504/ https://ncbi.nlm.nih.gov/pubmed/16157278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2005.08.022 |
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