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Evaluation of Paired-End Sequencing Strategies for Detection of Genome Rearrangements in Cancer

Paired-end sequencing is emerging as a key technique for assessing genome rearrangements and structural variation on a genome-wide scale. This technique is particularly useful for detecting copy-neutral rearrangements, such as inversions and translocations, which are common in cancer and can produce...

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書誌詳細
主要な著者: Bashir, Ali, Volik, Stanislav, Collins, Colin, Bafna, Vineet, Raphael, Benjamin J.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278375/
https://ncbi.nlm.nih.gov/pubmed/18404202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000051
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