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Evaluation of Paired-End Sequencing Strategies for Detection of Genome Rearrangements in Cancer
Paired-end sequencing is emerging as a key technique for assessing genome rearrangements and structural variation on a genome-wide scale. This technique is particularly useful for detecting copy-neutral rearrangements, such as inversions and translocations, which are common in cancer and can produce...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2278375/ https://ncbi.nlm.nih.gov/pubmed/18404202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000051 |
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