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IL-15 as a mediator of CD4(+) help for CD8(+) T cell longevity and avoidance of TRAIL-mediated apoptosis
CD4(+) helper T cells contribute to the induction and maintenance of antigen-specific CD8(+) T cells. Their absence results in short-lived antigen-specific CD8(+) T cells and defective secondary CD8(+) T cell responses because of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediat...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2278231/ https://ncbi.nlm.nih.gov/pubmed/18362335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801003105 |
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