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Coadministration of HIV vaccine vectors with vaccinia viruses expressing IL-15 but not IL-2 induces long-lasting cellular immunity

Vaccine efficacy is determined largely by cellular and humoral immunity as well as long-lasting immunological memory. IL-2 and IL-15 were evaluated in vaccinia vectors expressing HIV gp160 for the establishment of an effective vaccine strategy. Both IL-2 and IL-15 in the vaccinia vector induced stro...

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Autors principals: Oh, SangKon, Berzofsky, Jay A., Burke, Donald S., Waldmann, Thomas A., Perera, Liyanage P.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC152303/
https://ncbi.nlm.nih.gov/pubmed/12626740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0630592100
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