Development of Smallpox Vaccine Candidates with Integrated Interleukin-15 That Demonstrate Superior Immunogenicity, Efficacy, and Safety in Mice

The potential use of variola virus, the etiological agent of smallpox, as a bioterror agent has heightened the interest in the reinitiation of smallpox vaccination. However, the currently licensed Dryvax vaccine, despite its documented efficacy in eradicating smallpox, is not optimal for the vaccina...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Perera, Liyanage P., Waldmann, Thomas A., Mosca, Joseph D., Baldwin, Nicole, Berzofsky, Jay A., Oh, Sang-Kon
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Microbiology 2007
الموضوعات:
Vaccines and Antiviral Agents
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951366/
https://ncbi.nlm.nih.gov/pubmed/17553867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00538-07
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