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Development of Smallpox Vaccine Candidates with Integrated Interleukin-15 That Demonstrate Superior Immunogenicity, Efficacy, and Safety in Mice

The potential use of variola virus, the etiological agent of smallpox, as a bioterror agent has heightened the interest in the reinitiation of smallpox vaccination. However, the currently licensed Dryvax vaccine, despite its documented efficacy in eradicating smallpox, is not optimal for the vaccina...

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Bibliografiska uppgifter
Huvudupphovsmän: Perera, Liyanage P., Waldmann, Thomas A., Mosca, Joseph D., Baldwin, Nicole, Berzofsky, Jay A., Oh, Sang-Kon
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951366/
https://ncbi.nlm.nih.gov/pubmed/17553867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00538-07
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