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Molecular recognition of parathyroid hormone by its G protein-coupled receptor

Parathyroid hormone (PTH) is central to calcium homeostasis and bone maintenance in vertebrates, and as such it has been used for treating osteoporosis. It acts primarily by binding to its receptor, PTH1R, a member of the class B G protein-coupled receptor (GPCR) family that also includes receptors...

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Main Authors: Pioszak, Augen A., Xu, H. Eric
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278174/
https://ncbi.nlm.nih.gov/pubmed/18375760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801027105
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