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Regulation of Akt/PKB activity by P21-activated Kinase in Cardiomyocytes
Akt/PKB is a critical regulator of cardiac function and morphology, and its activity is governed by dual phosphorylation at active loop (Thr308) by phosphoinositide-dependent protein kinase-1 (PDK1) and at carboxyl-terminal hydrophobic motif (Ser473) by a putative PDK2. P21-activated kinase-1 (Pak1)...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2278035/ https://ncbi.nlm.nih.gov/pubmed/18054038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2007.10.016 |
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