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Prostaglandin E(2) stimulates expression of osmoprotective genes in MDCK cells and promotes survival under hypertonic conditions
The cells of the renal medulla produce large amounts of prostaglandin E(2) (PGE(2)) via cyclooxygenases (COX)-1 and -2. PGE(2) is well known to play a critical role in salt and water balance and maintenance of medullary blood flow. Since renal medullary PGE(2) production increases in antidiuresis, a...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Science Inc
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2277232/ https://ncbi.nlm.nih.gov/pubmed/17556390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.135178 |
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