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Prostaglandin E(2) stimulates expression of osmoprotective genes in MDCK cells and promotes survival under hypertonic conditions
The cells of the renal medulla produce large amounts of prostaglandin E(2) (PGE(2)) via cyclooxygenases (COX)-1 and -2. PGE(2) is well known to play a critical role in salt and water balance and maintenance of medullary blood flow. Since renal medullary PGE(2) production increases in antidiuresis, a...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Blackwell Science Inc
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2277232/ https://ncbi.nlm.nih.gov/pubmed/17556390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.135178 |
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