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Effects of a common human gene variant of extracellular superoxide dismutase on endothelial function after endotoxin in mice

A common gene variant in the heparin-binding domain (HBD) of extracellular superoxide dismutase (ECSOD) may predispose human carriers to ischaemic heart disease. We have demonstrated that the HBD of ECSOD is important for ECSOD to restore vascular dysfunction produced by endotoxin. The purpose of th...

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Bibliografiske detaljer
Main Authors: Lund, Donald D, Chu, Yi, Brooks, Robert M, Faraci, Frank M, Heistad, Donald D
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277153/
https://ncbi.nlm.nih.gov/pubmed/17717013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.140830
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