Effects of a common human gene variant of extracellular superoxide dismutase on endothelial function after endotoxin in mice

A common gene variant in the heparin-binding domain (HBD) of extracellular superoxide dismutase (ECSOD) may predispose human carriers to ischaemic heart disease. We have demonstrated that the HBD of ECSOD is important for ECSOD to restore vascular dysfunction produced by endotoxin. The purpose of th...

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Main Authors: Lund, Donald D, Chu, Yi, Brooks, Robert M, Faraci, Frank M, Heistad, Donald D
Formáid: Artigo
Teanga:Inglês
Foilsithe: Blackwell Publishing Ltd 2007
Ábhair:
Cardiovascular
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277153/
https://ncbi.nlm.nih.gov/pubmed/17717013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.140830
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