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Effects of a common human gene variant of extracellular superoxide dismutase on endothelial function after endotoxin in mice

A common gene variant in the heparin-binding domain (HBD) of extracellular superoxide dismutase (ECSOD) may predispose human carriers to ischaemic heart disease. We have demonstrated that the HBD of ECSOD is important for ECSOD to restore vascular dysfunction produced by endotoxin. The purpose of th...

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書誌詳細
主要な著者: Lund, Donald D, Chu, Yi, Brooks, Robert M, Faraci, Frank M, Heistad, Donald D
フォーマット: Artigo
言語:Inglês
出版事項: Blackwell Publishing Ltd 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277153/
https://ncbi.nlm.nih.gov/pubmed/17717013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.140830
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