Overexpression of pulmonary extracellular superoxide dismutase attenuates endotoxin-induced acute lung injury

PURPOSE: Superoxide is produced by activated neutrophils during the inflammatory response to stimuli such as endotoxin, can directly or indirectly injure host cells, and has been implicated in the pathogenesis of acute lung injury (ALI)/acute respiratory distress syndrome (ARDS). We wished to determ...

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Detalhes bibliográficos
Publicado no:Intensive Care Med
Main Authors: Hassett, Patrick, Curley, Gerard F., Contreras, Maya, Masterson, Claire, Higgins, Brendan D., O’Brien, Timothy, Devaney, James, O’Toole, Daniel, Laffey, John G.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
Assuntos:
Experimental
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7095197/
https://ncbi.nlm.nih.gov/pubmed/21755396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00134-011-2309-y
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