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Overexpression of pulmonary extracellular superoxide dismutase attenuates endotoxin-induced acute lung injury

PURPOSE: Superoxide is produced by activated neutrophils during the inflammatory response to stimuli such as endotoxin, can directly or indirectly injure host cells, and has been implicated in the pathogenesis of acute lung injury (ALI)/acute respiratory distress syndrome (ARDS). We wished to determ...

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Publicado en:Intensive Care Med
Main Authors: Hassett, Patrick, Curley, Gerard F., Contreras, Maya, Masterson, Claire, Higgins, Brendan D., O’Brien, Timothy, Devaney, James, O’Toole, Daniel, Laffey, John G.
Formato: Artigo
Idioma:Inglês
Publicado: Springer-Verlag 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7095197/
https://ncbi.nlm.nih.gov/pubmed/21755396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00134-011-2309-y
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