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Modelling experimental image formation for likelihood-based classification of electron microscopy data

The coexistence of multiple distinct structural states often obstructs the application of three-dimensional cryo-electron microscopy to large macromolecular complexes. Maximum likelihood approaches are emerging as robust tools for solving the image classification problems that are posed by such samp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Scheres, Sjors H. W., Núñez-Ramírez, Rafael, Gómez-Llorente, Yacob, Martín, Carmen San, Eggermont, Paul P. B., Carazo, José María
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277044/
https://ncbi.nlm.nih.gov/pubmed/17937907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2007.09.003
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