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Averaging of Electron Subtomograms and Random Conical Tilt Reconstructions through Likelihood Optimization

The reference-free averaging of three-dimensional electron microscopy (3D-EM) reconstructions with empty regions in Fourier space represents a pressing problem in electron tomography and single-particle analysis. We present a maximum likelihood algorithm for the simultaneous alignment and classifica...

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Bibliografski detalji
Glavni autori: Scheres, Sjors H.W., Melero, Roberto, Valle, Mikel, Carazo, Jose-Maria
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940245/
https://ncbi.nlm.nih.gov/pubmed/20004160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.10.009
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