Restriction of placental growth in sheep impairs insulin secretion but not sensitivity before birth

Restricted growth before birth is associated with impaired insulin secretion but with initially enhanced insulin sensitivity in early postnatal life, which then progresses to insulin resistance and impaired glucose homeostasis by adulthood. This suggests that prenatal restraint impairs insulin secre...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Owens, Julie A, Gatford, Kathryn L, De Blasio, Miles J, Edwards, Lisa J, McMillen, I Caroline, Fowden, Abigail L
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Science Inc 2007
Pynciau:
Renal And Endocrine
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276990/
https://ncbi.nlm.nih.gov/pubmed/17761772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.142141
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