Restriction of placental growth in sheep impairs insulin secretion but not sensitivity before birth

Restricted growth before birth is associated with impaired insulin secretion but with initially enhanced insulin sensitivity in early postnatal life, which then progresses to insulin resistance and impaired glucose homeostasis by adulthood. This suggests that prenatal restraint impairs insulin secre...

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Detalhes bibliográficos
Main Authors: Owens, Julie A, Gatford, Kathryn L, De Blasio, Miles J, Edwards, Lisa J, McMillen, I Caroline, Fowden, Abigail L
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
Assuntos:
Renal And Endocrine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276990/
https://ncbi.nlm.nih.gov/pubmed/17761772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.142141
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