Effect of placental restriction and neonatal exendin-4 treatment on postnatal growth, adult body composition, and in vivo glucose metabolism in the sheep

Intrauterine growth restriction (IUGR) increases the risk of adult type 2 diabetes (T2D) and obesity. Neonatal exendin-4 treatment can prevent diabetes in the IUGR rat, but whether this will be effective in a species where the pancreas is more mature at birth is unknown. Therefore, we evaluated the...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Liu, Hong, Schultz, Christopher G., De Blasio, Miles J., Peura, Anita M., Heinemann, Gary K., Harryanto, Himawan, Hunter, Damien S., Wooldridge, Amy L., Kind, Karen L., Giles, Lynne C., Simmons, Rebecca A., Owens, Julie A., Gatford, Kathryn L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631533/
https://ncbi.nlm.nih.gov/pubmed/26219868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00487.2014
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