Microscopic kinetic determinants of macroscopic currents: insights from coupling and uncoupling of GABA(A) receptor desensitization and deactivation

The time course of inhibitory postsynaptic currents (IPSCs) reflects GABA(A) receptor deactivation, the process of current relaxation following transient activation. Fast desensitization has been demonstrated to prolong deactivation, and these processes have been described as being ‘coupled’. Howeve...

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Detalhes bibliográficos
Main Authors: Bianchi, Matt T, Botzolakis, Emmanuel J, Haas, Kevin F, Fisher, Janet L, Macdonald, Robert L
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
Assuntos:
Cellular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276985/
https://ncbi.nlm.nih.gov/pubmed/17884921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.142364
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