Degradation of MEPE, DMP1, and Release of SIBLING ASARM-Peptides (Minhibins): ASARM-Peptide(s) Are Directly Responsible for Defective Mineralization in HYP

Mutations in PHEX (phosphate-regulating gene with homologies to endopeptidases on the X chromosome) and DMP1 (dentin matrix protein 1) result in X-linked hypophosphatemic rickets (HYP) and autosomal-recessive hypophosphatemic-rickets (ARHR), respectively. Specific binding of PHEX to matrix extracell...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Martin, Aline, David, Valentin, Laurence, Jennifer S., Schwarz, Patricia M., Lafer, Eileen M., Hedge, Anne-Marie, Rowe, Peter S. N.
Formato: Artigo
Idioma:Inglês
Publicado: The Endocrine Society 2008
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276704/
https://ncbi.nlm.nih.gov/pubmed/18162525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1205
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares