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ASARM peptides: PHEX-dependent and -independent regulation of serum phosphate

Increased acidic serine aspartate-rich MEPE-associated motif (ASARM) peptides cause mineralization defects in X-linked hypophosphatemic rickets mice (HYP) and “directly” inhibit renal phosphate uptake in vitro. However, ASARM peptides also bind to phosphate-regulating gene with homologies to endopep...

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Autors principals: David, Valentin, Martin, Aline, Hedge, Anne-Marie, Drezner, Marc K., Rowe, Peter S. N.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064126/
https://ncbi.nlm.nih.gov/pubmed/21177780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00304.2010
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