Gadd45β promotes hepatocyte survival during liver regeneration in mice by modulating JNK signaling

In the liver, the JNK cascade is induced downstream of TNF receptors (TNFRs) in response to inflammatory, microbial, and toxic challenges. Sustained activation of JNK triggers programmed cell death (PCD), and hepatocyte survival during these challenges requires induction of the NF-κB pathway, which...

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Bibliografiska uppgifter
Huvudupphovsmän: Papa, Salvatore, Zazzeroni, Francesca, Fu, Yang-Xin, Bubici, Concetta, Alvarez, Kellean, Dean, Kathryn, Christiansen, Peter A., Anders, Robert A., Franzoso, Guido
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2008
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276398/
https://ncbi.nlm.nih.gov/pubmed/18382767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33913
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