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Preferential Assembly of Epithelial Sodium Channel (ENaC) Subunits in Xenopus Oocytes: ROLE OF FURIN-MEDIATED ENDOGENOUS PROTEOLYSIS
The epithelial sodium channel (ENaC) is preferentially assembled into heteromeric αβγ complexes. The α and γ (not β) subunits undergo proteolytic cleavage by endogenous furin-like activity correlating with increased ENaC function. We identified full-length subunits and their fragments at the cell su...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2276330/ https://ncbi.nlm.nih.gov/pubmed/18195015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M707399200 |
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