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Incorporation of the δ-subunit into the epithelial sodium channel (ENaC) generates protease-resistant ENaCs in Xenopus laevis

The epithelial sodium channel (ENaC) is a critical regulator of vertebrate electrolyte homeostasis. ENaC is the only constitutively open ion channel in the degenerin/ENaC protein family, and its expression, membrane abundance, and open probability therefore are tightly controlled. The canonical ENaC...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Wichmann, Lukas, Vowinkel, Kirsty Sophia, Perniss, Alexander, Manzini, Ivan, Althaus, Mike
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5936831/
https://ncbi.nlm.nih.gov/pubmed/29576549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002543
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