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Preferential Assembly of Epithelial Sodium Channel (ENaC) Subunits in Xenopus Oocytes: ROLE OF FURIN-MEDIATED ENDOGENOUS PROTEOLYSIS

The epithelial sodium channel (ENaC) is preferentially assembled into heteromeric αβγ complexes. The α and γ (not β) subunits undergo proteolytic cleavage by endogenous furin-like activity correlating with increased ENaC function. We identified full-length subunits and their fragments at the cell su...

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書誌詳細
主要な著者: Harris, Michael, Garcia-Caballero, Agustin, Stutts, M. Jackson, Firsov, Dmitri, Rossier, Bernard C.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276330/
https://ncbi.nlm.nih.gov/pubmed/18195015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M707399200
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