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Role of the PI3-kinase/mTor pathway in the regulation of the stearoyl CoA desaturase (SCD1) gene expression by insulin in liver

The stearoyl-CoA desaturase 1 (SCD1) catalyzes the synthesis of monounsaturated fatty acids. This enzyme is a critical control point regulating hepatic lipogenesis and lipid oxidation. Therefore SCD1 may be a potential therapeutic target in the treatment of obesity and metabolic syndrome. Regulation...

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Autores principales: Mauvoisin, Daniel, Rocque, Gabriel, Arfa, Omar, Radenne, Anne, Boissier, Pomme, Mounier, Catherine
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Netherlands 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275876/
https://ncbi.nlm.nih.gov/pubmed/18481202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-007-0011-1
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