Targeting Stearoyl‐CoA Desaturase 1 Through PI3K‐AKT‐mTOR Signaling in Head and Neck Squamous Cell Carcinoma

Abstract Objective Stearoyl‐coenzyme A desaturase 1 (SCD1) is a key enzyme in fatty acid metabolism and has been implicated in cancer progression, including head and neck squamous cell carcinoma (HNSCC). The phosphoinositide 3‐kinase (PI3K)‐AKT‐mammalian target of rapamycin (mTOR) signaling pathway...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cheng‐Ming Hsu, Ming‐Yu Yang, Shun‐Fu Chang, Hui‐Chen Su
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Wiley 2025-04-01
Saila:OTO Open
Gaiak:
head and neck squamous cell carcinoma (HNSCC)
lipid metabolism
PI3K‐AKT‐mTOR signaling
stearoyl‐CoA desaturase 1 (SCD1)
therapeutic target
Sarrera elektronikoa:https://doi.org/10.1002/oto2.70143
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