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Enhancing therapeutic vaccination by blocking PD-1–mediated inhibitory signals during chronic infection
Therapeutic vaccination is a potentially promising strategy to enhance T cell immunity and viral control in chronically infected individuals. However, therapeutic vaccination approaches have fallen short of expectations, and effective boosting of antiviral T cell responses has not always been observ...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The Rockefeller University Press
2008
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2275378/ https://ncbi.nlm.nih.gov/pubmed/18332181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071949 |
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