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Substitution of a residue contacting the triphosphate moiety of the incoming nucleotide increases the fidelity of yeast DNA polymerase ζ
DNA polymerase ζ (pol ζ), which is required for DNA damage-induced mutagenesis, functions in the error-prone replication of a wide range of DNA lesions. During this process, pol ζ extends from nucleotides incorporated opposite template lesions by other polymerases. Unlike classical polymerases, pol...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2275142/ https://ncbi.nlm.nih.gov/pubmed/18263611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn023 |
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