Substitution of a residue contacting the triphosphate moiety of the incoming nucleotide increases the fidelity of yeast DNA polymerase ζ

DNA polymerase ζ (pol ζ), which is required for DNA damage-induced mutagenesis, functions in the error-prone replication of a wide range of DNA lesions. During this process, pol ζ extends from nucleotides incorporated opposite template lesions by other polymerases. Unlike classical polymerases, pol...

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Hlavní autoři: Howell, Craig A., Kondratick, Christine M., Washington, M. Todd
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2008
Témata:
Nucleic Acid Enzymes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275142/
https://ncbi.nlm.nih.gov/pubmed/18263611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn023
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