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Knockdown of TNFR1 by the sense strand of an ICAM-1 siRNA: dissection of an off-target effect
Tumor necrosis factor (TNF) initiates local inflammation by triggering endothelial cells (EC) to express adhesion molecules for leukocytes such as intercellular adhesion molecule-1 (ICAM-1 or CD54). A prior study identified siRNA molecules that reduce ICAM-1 expression in cultured human umbilical ve...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2275081/ https://ncbi.nlm.nih.gov/pubmed/18096615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm630 |
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