Transcriptional and phenotypic comparisons of Ppara knockout and siRNA knockdown mice

RNA interference (RNAi) has great potential as a tool for studying gene function in mammals. However, the specificity and magnitude of the in vivo response to RNAi remains to be fully characterized. A molecular and phenotypic comparison of a genetic knockout mouse and the corresponding knockdown ver...

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Detalhes bibliográficos
Main Authors: De Souza, Angus T., Dai, Xudong, Spencer, Andrew G., Reppen, Tom, Menzie, Ann, Roesch, Paula L., He, Yudong, Caguyong, Michelle J., Bloomer, Sherri, Herweijer, Hans, Wolff, Jon A., Hagstrom, James E., Lewis, David L., Linsley, Peter S., Ulrich, Roger G.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2006
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636368/
https://ncbi.nlm.nih.gov/pubmed/16945951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl609
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