Transcriptional and phenotypic comparisons of Ppara knockout and siRNA knockdown mice

RNA interference (RNAi) has great potential as a tool for studying gene function in mammals. However, the specificity and magnitude of the in vivo response to RNAi remains to be fully characterized. A molecular and phenotypic comparison of a genetic knockout mouse and the corresponding knockdown ver...

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Bibliografische gegevens
Hoofdauteurs: De Souza, Angus T., Dai, Xudong, Spencer, Andrew G., Reppen, Tom, Menzie, Ann, Roesch, Paula L., He, Yudong, Caguyong, Michelle J., Bloomer, Sherri, Herweijer, Hans, Wolff, Jon A., Hagstrom, James E., Lewis, David L., Linsley, Peter S., Ulrich, Roger G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2006
Onderwerpen:
RNA
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636368/
https://ncbi.nlm.nih.gov/pubmed/16945951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl609
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