Llwytho...

Alternative mRNA is favored by the A3 haplotype of the EPCR gene PROCR and generates a novel soluble form of EPCR in plasma

The endothelial cell protein C receptor also exists in soluble form in plasma (sEPCR), resulting from ADAM17 cleavage. Elevated sEPCR levels are observed in subjects carrying the A3 haplotype, which is characterized by a Ser219Gly substitution in the transmembrane domain, rendering the receptor more...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Saposnik, Beatrice, Lesteven, Elodie, Lokajczyk, Anna, Esmon, Charles T., Aiach, Martine, Gandrille, Sophie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275013/
https://ncbi.nlm.nih.gov/pubmed/18073349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-08-104968
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