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Insertion of EGFP into the replicase gene of Semliki Forest virus results in a novel, genetically stable marker virus
Alphavirus-based vector and replicon systems have been extensively used experimentally and are likely to be used in human and animal medicine. Whilst marker genes can be inserted easily under the control of a duplicated subgenomic promoter, these constructs are often genetically unstable. Here, a no...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Society for General Microbiology
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2274952/ https://ncbi.nlm.nih.gov/pubmed/17374766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.82436-0 |
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