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High Vascular Pressure–Induced Lung Injury Requires P450 Epoxygenase–Dependent Activation of TRPV4

High vascular pressure targets the lung septal network, causing acute lung injury. While calcium entry in septal endothelium has been implicated, the channel involved is not known. This study tested the hypothesis that the vanilloid transient receptor potential channel, TRPV4, is a critical particip...

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Detalhes bibliográficos
Main Authors: Jian, Ming-Yuan, King, Judy A., Al-Mehdi, Abu-Bakr, Liedtke, Wolfgang, Townsley, Mary I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2274943/
https://ncbi.nlm.nih.gov/pubmed/17962608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0192OC
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