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Functional coupling of TRPV4, IK, and SK channels contributes to Ca(2+)-dependent endothelial injury in rodent lung

Abstract. Our previous work has shown that the increased lung endothelial permeability response to 14,15-epoxyeicosatrienoic acid (14,15-EET) in rat lung requires Ca(2+) entry via vanilloid type-4 transient receptor potential (TRPV4) channels. Recent studies suggest that activation of TRPV4 channels...

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Detalhes bibliográficos
Publicado no:Pulm Circ
Main Authors: Lin, Mike T., Jian, Ming-Yuan, Taylor, Mark S., Cioffi, Donna L., Yap, Fui C., Liedtke, Wolfgang, Townsley, Mary I.
Formato: Artigo
Idioma:Inglês
Publicado em: University of Chicago Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449238/
https://ncbi.nlm.nih.gov/pubmed/26064452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/680166
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