TRPV4 channels augment macrophage activation and ventilator-induced lung injury

We have previously implicated transient receptor potential vanilloid 4 (TRPV4) channels and alveolar macrophages in initiating the permeability increase in response to high peak inflation pressure (PIP) ventilation. Alveolar macrophages were harvested from TRPV4(−/−) and TRPV4(+/+) mice and instille...

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Detalhes bibliográficos
Main Authors: Hamanaka, Kazutoshi, Jian, Ming-Yuan, Townsley, Mary I., King, Judy A., Liedtke, Wolfgang, Weber, David S., Eyal, Fabien G., Clapp, Mary M., Parker, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951075/
https://ncbi.nlm.nih.gov/pubmed/20562229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00315.2009
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