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Characterization of an antibody scFv that recognizes fibrillar insulin and beta-amyloid using Atomic Force Microscopy

Fibrillar amyloid is the hallmark feature of many protein aggregation diseases, such as Alzheimer’s and Parkinson’s Diseases. A monoclonal single chain variable fragment (scFv) targeting insulin fibrils was isolated using phage display technology and an atomic force microscopy (AFM) mica substrate....

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Sonraí Bibleagrafaíochta
Main Authors: Marcus, W. D., Wang, H., Lindsay, S. M., Sierks, M. R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2274779/
https://ncbi.nlm.nih.gov/pubmed/18201941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2007.11.003
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