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Engineering membrane protein overproduction in Escherichia coli

Membrane proteins play a fundamental role in human disease and therapy, but suffer from a lack of structural and functional information compared to their soluble counterparts. The paucity of membrane protein structures is primarily due to the unparalleled difficulties in obtaining detergent-solubili...

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Detalhes bibliográficos
Main Authors: Molina, Daniel Martinez, Cornvik, Tobias, Eshaghi, Said, Haeggström, Jesper Z., Nordlund, Pär, Sabet, Marina Ignatushchenko
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2271156/
https://ncbi.nlm.nih.gov/pubmed/18305199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073242508
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