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Suppressing glucose uptake and acetic acid production increases membrane protein overexpression in Escherichia coli

BACKGROUND: The production of integral membrane spanning proteins (IMP's) constitutes a bottleneck in pharmaceutical development. It was long considered that the state-of-the-art was to produce the proteins as inclusion bodies using a powerful induction system. However, the quality of the prote...

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Detalhes bibliográficos
Main Authors: Bäcklund, Emma, Ignatushchenko, Marina, Larsson, Gen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121589/
https://ncbi.nlm.nih.gov/pubmed/21586123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-10-35
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