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Metabolic Engineering for l-Glutamine Overproduction by Using DNA Gyrase Mutations in Escherichia coli
An l-glutamine-overproducing mutant of an Escherichia coli K-12-derived strain was selected from randomly mutagenized cells in the course of l-alanyl-l-glutamine strain development. Genome-wide mutation analysis unveiled a novel mechanism for l-glutamine overproduction in this mutant. Three mutation...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3623149/ https://ncbi.nlm.nih.gov/pubmed/23455340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.03994-12 |
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