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Epigenetic Analysis of the Human Alpha- and Beta-Globin Gene Clusters

K562 erythroleukemia cells have been widely used as a model for the study of globin gene regulation. A number of agents have been shown to activate or suppress globin gene expression in these cells. However, the molecular effects of these agents on the epigenetic configuration of the α- and γ-globin...

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Autori principali: Fathallah, Hassana, Portnoy, Gregory, Atweh, George F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2270787/
https://ncbi.nlm.nih.gov/pubmed/18029204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2007.08.001
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